North Central London
Joint Formulary
 
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5 Infections

Prescribing of systemic antimicrobials is 'protected'. All prescribing MUST be in accordance with the Trust Antimicrobial Policy and in conjunction with local antimicrobial guideline:

05-02 Antifungal drugs

Amphotericin infusion Fungizone®
Formulary

Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • Not for intravenous use
    • Microbiology/ID approval only
  • RNOH:
    • Non-formulary
  • UCLH:
    • Approved for:
      • Cryptococcosis – treatment (Restricted to Microbiology approval)
      • Serious fungal infections (Restricted to Microbiology approval for intraventricular disease)
  • WH:
    • Non-formulary

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Amphotericin liposomal infusion AmBisome®
Restricted

Provider notes

  • NMUH:
    • As per Trust Guidelines
  • RFL:
    • Restricted to OLT prophylaxis (2nd transplant/hepatic artery thrombosis)
    • Microbiology/ID approval required for all other indications
  • RNOH:
    • Microbiology approval only
  • UCLH:
  • WH:
    • Microbiology approval only

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Fluconazole
Restricted

Provider notes

  • NMUH:
    • Infusion restricted to Microbiology Consultants use only
  • RFL:
    • No restriction stated
  • RNOH:
    • No restriction stated
  • UCLH:
  • WH:
    • Restricted antifungal. Microbiology approval only

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Flucytosine infusion
Restricted

Provider notes

  • NMUH:
    • Restricted to Microbiology Consultants use only
  • RFL:
    • Microbiology / ID approval required 
  • RNOH:
    • Non-formulary  
  • UCLH:
  • WH:
    • Microbiology approval only

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Griseofulvin
Formulary

Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • No restriction stated
  • RNOH:
    • Non-formulary  
  • UCLH:
  • WH:
    • No restriction stated

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Isavuconazole capsules/infusion
Formulary

Approved for treatment of proven or probable invasive aspergilosis or mucomycosis where other antifungals are not appropriate (JFC August 2020)

Provider notes

  • NMUH:
    • As per JFC decision above
    • On microbiology recommendation ONLY
  • RFL:
    • Non-formulary
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary

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Itraconazole
Restricted

Provider notes

  • NMUH:
    • No restriction stated
  • RFL:
    • Oral: Restricted to Dermatology; HIV; Haematology. ID/Microbiology approval for all other indications.
    • Intravenous: Microbiology/ID approval
  • RNOH:
    • Microbiology approval only
  • UCLH:
  • WH:
    • For restricted indications as per Trust guidelines or Microbiology advice

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Posaconazole
Restricted

Provider notes

  • NMUH:
    • Liquid: Restricted to Haematology and Oncology for prophylaxis; Microbiology approval required for treatment doses and all other indications
    • Tablets: Microbiology/ID approval required
  • RFL:
    • Liquid: Restricted to Haematology and Oncology for prophylaxis; Microbiology approval required for treatment doses and all other indications
    • Tablets: Microbiology/ID approval required
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • Non-formulary

Restricted Drug GP - Red View adult BNF  View SPC online  View childrens BNF  HCD
Terbinafine tabs
Restricted

Provider notes

  • NMUH:
    • Restricted to Dermatology use only
  • RFL:
    • No restriction stated
  • RNOH:
    • No restriction stated
  • UCLH:
  • WH:
    • No restriction stated

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Voriconazole
Restricted

Provider notes

  • NMUH:
    • Microbiology approval required
    • See MHRA Drug Safety Updates
  • RFL:
    • Microbiology approval required 
  • RNOH:
    • Microbiology approval required
  • UCLH:
  • WH:
    • Check with Microbiology

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Flucytosine tablets
Formulary

Provider notes

  • NMUH:
    • Non-formulary
  • RFL:
    • Microbiology / ID approval required
  • RNOH:
    • Non-formulary
  • UCLH:
  • WH:
    • 500mg tablets

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Amphotericin lipid complex infusion Abelcet®
Non Formulary

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Ketoconazole tablets
Non Formulary

NOTE: There is more than one monograph for this medicine, click here to search for formulary status and its use for other indications. 

License withdrawn for this indication


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